Did you know that every cell has 15,000 biochemical interactions every second? And, did you know that there are, on average, 38 billion cells in a human body? 38 billion cells, each processing 15,000 chemical interactions per second. That’s a lot of processes per second! And how does the body keep it all working effectively? Cannabinoids.
Yep. Every cell has cannabinoid receptors–both on the exterior and interior of the cell. The cannabinoids connect to the cell’s physiology via receptor sites and modulate the 15,000 biochemical interactions to make sure they are in harmony with each other and maintain the homeostasis of a healthy body and balanced (ie happy) mental and emotional attitude. In fact, the current hypothesis amongst scientists studying the Endocannabinoid System is that a deficiency of cannabinoids is the very first indicator of declining health. Eventually disease follows if not restored.
Cannabinoids could, indeed, be called “guardian” molecules that protect all of the systems and tissues in the body from harm and damage through this subtle signaling system.
For example, in our modern “civilized” eating style more and more people are developing gut permeability or “leaky gut.” The infinitesimally small openings allow pathogens into the blood that overstimulate the immune system, causing autoimmune conditions–again, more and more documented every day as statistical evidence shows autoimmune disease numbers rising dramatically in the last decade. Cannabinoids in the gut, signal the cells to rebuild the broken junctures, helping to heal the permeability. And, as well, cannabinoids attach to the receptors of immune system cells and “down-regulate” them to stop attacking the body’s own cells. Truly a guardian for anyone with an autoimmune condition, right?
The same is true for neural health. Studies indicate that people with head injuries suffer fewer ramifications if medical cannabis therapy is in play. As well, studies show that stroke victims who use medical cannabis recover faster, and–if they were using medical cannabis before the stroke occurred–they had fewer ongoing complications as well. The proof of how cannabinoids guard and protect the brain is also evident in how effectively cannabinoids lessen seizure activity, decrease pain signaling, and balance neurotransmitter activity.
These are just a few examples. The list is extensive and growing as more medical research is done. Every system in the body, every tissue in the body, every cell in the body… all of them are positively impacted to better balance and harmony by the presence of cannabinoids. These cannabinoids can come from both the body’s own mechanisms (known as endocannabinoids) or by the use of phyto-cannabinoids from plants (most commonly, the cannabis plant.)
So, how’s your health and happiness balance? If you feel full of vitality and eager for the adventures of life, you can assume your body is fully functioning with its own endogenous cannabinoids. If you are feeling the effects of aging, or a slow decline, or feelings of anxiety or depression. then it’s safe to assume your own internal system is deficient. You could take action to restore it by either adding phyto-cannabinoids into your supplemental plan or by taking action to reduce the lifestyle factors that have contributed to its decline. (see: Assess the Health of Your Endocannabinoid System)
If you currently have a chronic condition, then we can extrapolate that your endocannabinoid system has been deficient for some time. Can you imagine what it would be like to feel vital and happy and eager for the adventure of life again? If it were possible that cannabinoids could be your guardian angel molecules, would you welcome their help and support?
The last question may be the most important. Tell me what you think in the comment section below.
I just watched a tv show about the benefits of cannabinoids for CTE and football players. It really is amazing the variety of things which are affected by cannabinoids! I’m curious about the chemistry of how the cannabinoids act as a neuroprotector.
Great question, Alan! I’m going to put my “scientist hat” on and see if I can answer your question…
Damage to the brain’s neural tissue is caused by the over production of glutamate which, in turn, increases the amount of calcium influx into the neurons… and this is a key factor in damage caused to neurons (in addition, of course, to blood loss to the brain and/or oxygen loss to the brain)
Cannabinoids create homeostasis amongst neurotransmitters and naturally down-regulate high levels of glutamate, reducing the amount of calcium influx. See how that is?
Here’s the more scientific explanation:
“The brain has many redundant blood supplies, which means that its tissue is seldom completely deprived of oxygen, even during acute ischemic events caused by thromboembolic events or trauma. A combination of the injury of hypoxia with the added insult of glutamate toxicity is therefore believed to be ultimately responsible for cellular death. Hence if the additive insult of glutamate toxicity can be alleviated, neurological damage could also be lessened. Anti-oxidants and anti-inflammatory agents have been proposed to reduce damage, but they often have poor access to structures such as the brain (which are protected by the blood brain barrier)”
https://www.procon.org/files/United%20States%20Patent%206630507.pdf
My answer to your last question is a resounding “yes!” I love the image of cannabinoids as a guardian angel! And I love the effects I’ve had so far from taking a phyto-cannabinoid supplement: stopped muscle cramps, helps me sleep better, and is clearing up inflammation from arthritis.
Me, too, Marion! 😀